Bone lesions are abnormalities in bone tissue that may disrupt normal body processes or create structural deficiencies. These sorts of abnormalities have a broad range of potential underlying causes.
Bone lesions may result from the growth of cancerous (malignant) bone tumors, according to the U.S. National Library of Medicine. Examples of bone cancers include osteosarcoma, Ewing’s sarcoma and multiple myeloma.
Bone lesions may also result from the growth of noncancerous (benign) bone tumors. The Merck Manuals Online Medical Library and the U.S. National Library of Medicine cite examples of benign bone lesions that include osteoid osteomas, osteoblastomas, unicameral or aneurysmal bone cysts and fibromas.
Certain infections may also lead to the formation of bone lesions, notes the U.S. National Library of Medicine. Potential causes here include mycobacterial infections, coccidiomycosis and histoplasmosis.
The U.S. National Library of Medicine cites other potential causes of bone lesions that include osteomyelitis, osteomalacia, rickets and osteitis fibrosa.
The U.S. National Library of Medicine notes that certain causes of bone lesions may coexist with disorders that cause blood-clotting abnormalities.